2022

Author(s): Charles-Nino CL, Loera A, Medina-Guerrero EO, Sanroman-Loza EA, Toledo B, Pedroza-Roldan C

Purpose of Review Sporotrichosis is a disease caused by fungi belonging to the genus of Sporothrix. Infection with this fungus in humans causes symptoms that range from cutaneous to systemic. Moreover, immunocompromised patients are more susceptible to the severity of the infection. The fungus can be found in various organic materials such as plants and soil. Until the end of the 1990s, sporotrichosis was considered an occupational and work-related disease, and high-risk individuals were those who had permanent contact with these materials. However, what is the role of animals in the transmission of the fungus to humans? What role is the environment playing in this transmission process? This literature review aims to compile knowledge to answer these questions. Recent Findings Epidemiological studies have shown an increase in the cases of infection in domestic animals with the fungus, which have transmitted the infection to humans. This is to be expected due to changes in human behavior towards animals, which now have a very close relationship. Additionally, soil and water contamination with the fungus has increased, perhaps due to changes in land use, increased humidity, and temperature associated with climate change. Summary The endemic regions of this fungus are characterized by warm or tropical climates, which favor disease transmission through direct or indirect contact with animals or contaminated soil. The climate change that our planet is currently experiencing has had an impact on various regions of the world where infected cases of Sporothrix spp. in humans have increased. Due to this, it is relevant to promote research associated with the prevalence of sporotrichosis in humans and animals, as well as soil contamination monitoring in order to prevent infection.

DOI: https://dx.doi.org/10.1007/s40475-022-00250-z