Africa is most vulnerable to climate change, although it makes the least contribution to factors that result in global and regional climatic changes. High levels of vulnerability and low adaptive capacity across the continent have been linked to, among other things, poverty. This paper discusses and analyses the relationship between climate change and poverty in Africa. It investigates the relationship between climate change and poverty patterns in Africa, analyses the resultant impact, and discusses potential adaptation policies for moderating the consequences of climatic changes on poverty in the region. The record shows that climate change is happening. What is not discussed or is little researched is the potential devastating impact of climate change on socio-economic development in Africa and the policy measures available to the continent for adaptation.