Racial and ethnic minority and lower-income groups are disproportionately affected by environmental hazards and suffer worse health outcomes than other groups in the United States. Relative to whites and higher-income groups, racial-ethnic minority and lower-income Americans also frequently express greater concern about high-profile global environmental threats like climate change, but they are widely misperceived as being less concerned about these issues than white and higher-income Americans. We use new survey research to explore public perceptions of COVID-19-another global threat marked by substantial racial, ethnic, and class disparities-finding a distinct pattern of misperceptions regarding groups' concerns. We then discuss how these misperceptions represent a unique form of social misinformation that may pose a threat to science and undermine the cooperation and trust needed to address collective problems.