Due to global warming, increase in air temperature is a growing concern at present. This rise in temperature may cause mild to severe thermal discomfort and heat related hazards mostly for the people who are engaged in outside activities throughout the day. The present study shows the inter-spatial monthly distribution of thermal patches over major stations of Madhya Pradesh, viz., Bhopal, Gwalior, Indore, Jabalpur, Hoshangabad, Rewa, Ratlam, Ujjain, Dhar etc. In this study, various Heat Indices applicable for tropical climate including Wet Bulb Globe Temperature (WBGT) are used to estimate the thermal stress by analyzing the meteorological data of Summer-2018 in Madhya Pradesh. Study was carried out for computing indoor, shady and outdoor heat stress separately and heat transfer rates to identify the places vulnerable to severe heat stroke in the month of March, April and May in 2018.It is observed that declaration of heat wave alone at any station is not sufficient for the administration and health organizations to take precautionary actions; also, discomfort indices should be referred for impact based monitoring and making work schedules. It is found that March and April fall in the partial discomfort category for at least half of the districts in Madhya Pradesh. It is interesting to note that several districts fall in discomfort category in outdoor conditions but not in indoor or shady conditions in May month. Severe stresses are observed mainly in the West and Central Madhya Pradesh during April and May months. Comparison of various Heat Indices is too performed along with computing Tropical Summer Index (TSI) and Apparent Temperature (AT) to indicate real feel-like temperatures in Madhya Pradesh during extreme temperature events.