The Global Strategic Preparedness, Readiness and Response Plan (SPRP) to tackle dengue and other Aedes-borne arboviruses aims at reducing the burden of disease, suffering and deaths from dengue and other Aedes-borne arboviral diseases such as Zika and chikungunya, by fostering a global coordinated response. The Plan outlines priority actions to control transmission and offers recommendations to affected countries across various sectors, including disease surveillance, laboratory activities, vector control, community engagement, clinical management, and research and development, through a whole-of-society and regional approach.