If the alarming climate change and sea-level rise scenario occurs without coping solutions, it will greatly affect the socio-economic development and the environment of the the Mekong River Delta region. Recognizing this, the Government has soon developed both policies and action plans to adapt to climate change for the region. However, the policies and programs to cope with climate change are still inadequate and limited. In order to complete the climate change adaptation policies in the Mekong Delta in the current context, the Government and localities in the region need to implement more comprehensive and practical solutions for it.