INTRODUCTION: Climate change exacerbates existing sociopolitical and economic vulnerabilities, undermining livelihoods, inflating the risk of conflict, and making it difficult for people to remain stable. In 2019, around 25 million new displacements occurred due to natural disasters. This review aims to summarize the existing evidence regarding the impact of climate change on the health of African immigrants. METHODS: Nine databases were systematically searched using a strategy developed in collaboration with a subject librarian. Potentially relevant articles were identified, screened, and reviewed by at least two reviewers, with a third reviewer resolving conflicts where necessary. Data were extracted from relevant articles using a standardized form. RESULTS: Seven studies (three cross-sectional, two qualitative, one cohort, and one need assessment report) were identified; they included different categories of African migrants and reported on various aspects of health. The included articles report on climate change, e.g., flooding, drought, and excess heat, resulting in respiratory illness, mental health issues, malnutrition, and premature mortality among African immigrants. CONCLUSION: This review suggests climate change adversely affects the physical, mental, and social health of African immigrants. It also highlights a knowledge gap in evidence related to the impact of climate change on the health of African immigrants.