Children are disproportionately vulnerable to the impacts of climate change because of physiological, developmental, behavioral, and social factors. In addition, they are likely to bear the consequences of these impacts over their life course. This paper reviews the health impacts of climate change on children's health, highlights specific vulnerabilities and offers recommendations to pediatric health care professionals for mitigation, adaptation, policy, and personal interventions to address our changing climate. Health care professionals can help families in mitigation and adaptation strategies to reduce their risk from climate change.