Already challenged by a highly variable climate, senegal and its people are likely to become more vulnerable to health risks as climate change alters rainfall and temperature patterns. This report, supported by the USAID-funded ATLAS (Climate Change Adaptation, Thought Leadership, and Assessments) activity, examines how future climate impacts may harm health outcomes in this West African nation of 14.5 million people. Through detailed analysis of anticipated climate changes, the report looks region by region at the potential for increased risks related to waterborne, vector-borne, and neglected tropical diseases, as well as declining nutrition. This study is the first piece of a three-part series that will include an assessment of climate change and health in Mozambique and a thought leadership paper comparing approaches to assessments of health and climate change in Africa.