Non-CO(2) air pollutants from motor vehicles have traditionally been controlled to protect air quality and health, but also affect climate. We use global composition-climate modelling to examine the integrated impacts of adopting stringent European on-road vehicle-emission standards for these pollutants in 2015 in many developing countries. Relative to no extra controls, the tight standards lead to annual benefits in 2030 and beyond of 120,000-280,000 avoided premature air pollution-related deaths, 6.1-19.7 million metric tons of avoided ozone-related yield losses of major food crops, $1.50.6-2.4 trillion avoided health damage and $US1.1-4.3 billion avoided agricultural damage, and mitigation of 0.20 (+0.14/-0.17)degrees C of Northern Hemisphere extratropical warming during 2040-2070. Tighter vehicle-emission standards are thus extremely likely to mitigate short-term climate change in most cases, in addition to providing large improvements in human health and food security. These standards will not reduce CO(2) emissions, however, which is required to mitigate long-term climate change.