BACKGROUND: The empirical assessment of the health outcomes associated with migration caused by climate change is still unclear. However, health outcomes in the early stages are expected to be similar to the health outcomes associated with refugees. The objective of the present study was a systematic review of the health effects of migration caused by climate change. METHODOLOGY: A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Online databases (PubMed, Scopus, Web of Science, and Google Scholar) were used to identify papers published that evaluated the health effects of migration caused by climate change. The search, article selection, and data extraction were carried out by two researchers independently. All English-language articles on the health effects of migration caused by climate change were included in this study. RESULTS: An analysis of the complex ways in which climate change influences populations can be facilitated using a three-class classification: compulsory displacement, resettlement planning, and migration. Subsequent to climate changes, other changes, and environmental deficiencies, compulsory displacement may occur in case of inadequacy of compatibility responses. A part of migration-related health outcomes caused by climate change is from displacement from rural to urban areas, especially in developing countries. There is significant documentation on health and livelihood inequalities between migrant groups and host populations in developed countries. CONCLUSION: If climate change continues in its current direction, it is likely that the number of refugees and crises will increase in the coming decades. Although the domain and the extent of health hazards caused by the displacement of the population associated with climate change cannot be clearly predicted, by reducing global greenhouse gas emissions, along with social and environmental adaptation strategies, migration caused by climate change, health risks and its relevant crises can be greatly reduced.