Pastoral women in the semi-arid rangelands of East Africa are significantly burdened by the vulnerability to and responsibility for responding to changing climates. Consequently, understanding how adaptation and coping strategies impact pastoral women's well-being is critical for supporting the climate resilience of communities and the landscapes on which they rely. We used a household survey, guided by a multi-dimensional framework of well-being, to investigate how the use of drought-related coping and adaptation strategies by Samburu households influenced livestock loss and women's well-being in northern Kenya. Coping and adaptation strategies predicted numerous social-cognitive components of well-being, although not livestock loss. We conjecture these results are a product of a gendered division of labor within households and the community. We argue that interventions aimed at supporting drought resilience must consider the gendered implications of climate response strategies, multiple indicators for evaluation, and the influence of community and place.