The partnership between the Resilient Cities Network and Yale University was formed to explore co-benefits of climate and health resilience and identify evidence-based interventions. As a first step in this partnership, we conducted a brief survey among city leaders in 2023 to identify priority areas in climate health, capacity and existing infrastructure, and opportunities for collaboration. More than 50% of the world’s population lives in urban areas, projected to increase to 70% by 2050. City residents report greater life satisfaction and have greater access to services, technology, and economic opportunities than non-urban dwellers. Despite these benefits, urban residents face substantial challenges to achieving health and well-being. Those in cities experience greater exposure to air pollution and extreme heat, both of which are associated with adverse respiratory, cardiovascular, and mental health outcomes.