The IPBES nexus scoping report provides an in-depth framework for understanding and addressing the interconnected challenges of biodiversity, food systems, water resources, human health, and climate change. It emphasizes the importance of integrated approaches to tackle these critical global issues, fostering sustainability and resilience. The report highlights the need for collaborative action, innovative solutions, and policy alignment to mitigate risks and promote harmonious coexistence with nature while addressing human needs. This foundational document guides stakeholders in exploring strategies to achieve impactful, long-term outcomes.