In the recent years, the effects of extreme climate phenomena (mainly heat-related) on agricultural crops, infrastructure and human health have become increasingly severe as a result of their complex interactions with the particularities of the urban/rural habitat, as well as the social and economic factors. In Romania, heat-related phenomena (e.g. drought, heat waves) are affecting wide areas in the southern half of the territory where the study area (Bucharest Metropolitan Area) lies. The paper aims to develop a multi-criteria vulnerability assessment using both quantitative and qualitative methods. 23 indicators were selected and processed in order to assess various components of socio-economic and environmental vulnerability to heat-related phenomena using the statistical data available at local administrative units (LAU). The indicators were grouped into the three key components of vulnerability (potential exposure, sensitivity and adaptive capacity) on two dimensions (socio-economic and environmental) resulting two indexes: Socio-Economic Vulnerability Index (SEVI) and Environmental Vulnerability Index (EVI). Finally, an integrated Heat Vulnerability Index (HVI) (using Hull score, average 50 and standard deviation 14) was computed.