Because of the human health consequences and association with consumption of raw seafood, state managers are responsible for regulating the shellfish industry to reduce consumer risk. Knowing where and when to expect elevated concentrations of Vibrio, and environmental conditions that promote rapid growth can inform both management and individual grower harvest decision making. Over the past decade, the scientific community has made major strides in modeling and forecasting Vibrio and our environment. By combining state of the art hydrodynamic models with specific algorithms for Vibrio, we can provide early warning of these potential coastal hazards. An assortment of predictive models and weather related tools have been assembled, primarily related to issues surrounding safe harvest of shellfish around the nation. In partnership with the US Food and Drug Administration (USFDA), state and academic partners, NOAA is working continuously through the Ecological Forecasting Roadmap to verify and improve model accuracy and resolution, and transition them to a state of operations.