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Epidemiological characteristics and climatic variability of viral meningitis in Kazakhstan, 2014-2019

BACKGROUND: The comprehensive epidemiology and impact of climate on viral meningitis (VM) in Kazakhstan are unknown. We aimed to study the incidence, in-hospital mortality and influence of climatic indicators on VM from 2014 to 2019. METHODS: Nationwide electronic healthcare records were used to explore this study. ICD-10 codes of VM, demographics, and hospital outcomes were evaluated using descriptive statistics and survival analysis. RESULTS: During the 2014-2019 period, 10,251 patients with VM were admitted to the hospital. 51.35% of them were children, 57.85% were males, and 85.9% were from the urban population. Enteroviral meningitis was the main cause of VM in children. The incidence rate was 13 and 18 cases per 100,000 population in 2014 and 2019, respectively. Case fatality rate was higher in 2015 (2.3%) and 2017 (2.0%). The regression model showed 1°C increment in the daily average temperature might be associated with a 1.05-fold (95% CI 1.047-1.051) increase in the daily rate of VM cases, 1hPa increment in the average air pressure and 1% increment in the daily average humidity might contribute to a decrease in the daily rate of VM cases with IRRs of 0.997 (95% CI 0.995-0.998) and 0.982 (95% CI 0.981-0.983), respectively. In-hospital mortality was 35% higher in males compared to females. Patients residing in rural locations had a 2-fold higher risk of in-hospital death, compared to city residents. Elderly patients had a 14-fold higher risk of in-hospital mortality, compared to younger patients. CONCLUSION: This is the first study in Kazakhstan investigating the epidemiology and impact of climate on VM using nationwide healthcare data. There was a tendency to decrease the incidence with outbreaks every 5 years, and mortality rates were higher for Russians and other ethnicities compared to Kazakhs, for males compared to females, for elder patients compared to younger patients, and for patients living in rural areas compared to city residents. The climatic parameters and the days of delay indicated a moderate interaction with the VM cases.

Effects of air temperature on the number of ambulance calls for asthma during cold season in Nur-Sultan- The second coldest capital in the world

Deleterious effect of cold on overall mortality is well-established. We studied associations between the air temperature and the number f ambulance calls for asthma in Nur-Sultan, Kazakhstan – the second coldest capital in the world. Daily counts of ambulance calls for asthma in Nur-Sultan for the cold seasons (October-March) 2006-2010 were obtained from the Municipal Ambulance Station. Associations between the number of calls and mean and minimum apparent temperatures (average for lags 0-15) were studied using first-order Poisson auto-regression models controlling for wind speed and effects of month, year, weekends and holidays. Altogether, there were 7373 ambulance calls for asthma during the study period. An inverse association between minimum apparent temperature and the number of calls was observed for the age-group 60 years and older. A decrease of the minimum apparent temperature by 1 °C was associated with an increase in the number of calls by 1.7% (95% CI: 0.1%-3.3%) across the whole temperature spectrum. No associations in other age groups were found. Our results suggest an inverse association between the average 15-day lag minimum apparent temperature and the number of ambulance calls during the cold season in Nur-Sultan, but this is limited to the oldest age-group.

Zero regrets: scaling up action on climate change mitigation and adaptation for health in the WHO European Region, second edition. Key messages from the Working Group on Health in Climate Change

Human Climate Horizons (HCH)

Developing spatial agricultural drought risk index with controllable geo-spatial indicators: A case study for South Korea and Kazakhstan

Constant environmental degradation and increased frequency and severity of natural disasters have been evident over the past few decades worldwide. As such, scientific tools to predict and assess risks keep being developed. Assessing disaster risk is an important task in supporting the transition to a sustainable society. However, as disasters and systems become more complex, disaster models combining diverse aspects including climatic, social, economic, and environmental factors are necessary. For this study, we set a model using the concept of risk by identifying hazards, exposure, and vulnerability. Here, the vulnerability was classified into two domains, sensitivity and adaptive capacity, and two spheres, natural/built environment and human environment. Also, we stressed that controllable geo-spatial indicators should be included in risk assessments to effectively reduce risk and implement adequate spatio-temporal actions. The approach of this study was applied to Kazakhstan and South Korea as a pilot study to develop Agricultural Drought Risk Index (ADRI) and maps. As a result, the agricultural drought risk could be analyzed for South Korea and Kazakhstan. In addition, we performed additional spatial analyses at a reasonable scale for practical use. It was concluded that prioritizing risk areas at administrative and site level could contribute in decision and policy-making for risk reduction. Furthermore, spatial data availability and quality were found to be significant in assessing disaster risk.

Description and attribution analysis of the 2017 spring anomalous high temperature causing floods in Kazakhstan

It is speculated that floods in many areas of the world have become more severe with global warming. This study describes the 2017 spring floods in Kazakhstan, which, with about six people dead or missing, prompted the government to call for more than 7,000 people to leave their homes. Then, based on the Climatic Research Unit (CRU), the NCEP/NCAR Reanalysis 1, and the Coupled Model Intercomparison Project 5 (CMIP5) simulations, the seasonal trends of temperature were calculated using the linear least-squares regression and the Mann-Kendall trend test. The correlation between the surface air temperature and atmospheric circulation was explored, and the attributable risk of the 2017 spring floods was evaluated using the conventional fraction of the attributable risk (FAR) method. The results indicate that the north plains of Kazakhstan had a higher (March-April) mean temperature anomaly compared to the south plains, up to 3 degrees C, relative to the 1901 – 2017 average temperature. This was the primary cause of flooding in Kazakhstan. March and April were the months with a higher increasing trend in temperature from 1901 to 2017 compared with other months. In addition, a positive anomaly of the geopotential height and air temperature for the March-April 2017 period (based on the reference period 1961 – 1990) was the reason for a warmer abnormal temperature in the northwest region of Kazakhstan. Finally, the FAR value was approximately equal to 1, which supported the claim of a strong anthropogenic influence on the risk of the 2017 March-April floods in Kazakhstan. The results presented provide essential information for a comprehensive understanding of the 2017 spring floods in Kazakhstan and will help government officials identify flooding situations and mitigate damage in future.

The effect of ambient air temperature and precipitation on monthly counts of salmonellosis in four regions of Kazakhstan, Central Asia, in 2000-2010

Modeling the potential distribution of Bacillus anthracis under multiple climate change scenarios for Kazakhstan

Flash Flood Guidance System with Global Coverage (FFGS)