Climate change is perhaps the topmost challenge of our time. To prevent climate change from severely impacting almost every facet of life on the planet, scientific consensus points to a need to reduce the emissions of greenhouse gases (GHG), measured in terms of CO2 equivalents (CO2e), by as much as 80 percent by 2050. So far the focus has centered on incremental reductions of CO2 e emissions in areas in which they are highest, without negatively impacting the economy. But there is also a large untapped opportunity to drive economic growth by applying transformative solutions. In this paper, a method to evaluate CO2e reduction in the e-health applications is presented.