Groundwater is the major source of water for drinking and irrigation purposes in and around Hua County, Shaanxi Province, China. The main purposes of this research is to evaluate the groundwater quality in the rainy and dry seasons of Hua County and analyze the causes of seasonal differences and determine the areas with serious pollution. Groundwater quality was assessed in this study using entropy water quality index (EWQI) and some graphical approaches such as Gibbs and Piper diagrams. The contour maps of groundwater quality were drawn by Geographical Information System (GIS). According to the obtained results, the locations where groundwater quality was rated as excellent or good in both wet and dry seasons were mainly in the north and east of the research area. COD and NO3- are the parameters that have the most serious negative effect on water quality. The dominant factors influencing groundwater chemical evolution in the study area were rock weathering and dissolution, and the precipitation and evaporation during the wet and dry seasons do not cause significant changes in groundwater chemistry. Adults' health risks results revealed that 27.69% and 52.31% of the groundwater samples exceeded the acceptable limit for non-carcinogenic risk in the wet and dry season, respectively, while for children the ratios are 30.16% and 47.62%, respectively. The contributive percentages of nitrate, fluoride and nitrate to the total risk are 61.29%, 28.71% and 10.00% in the wet season and 68.84%, 20.85% and 10.31% in the dry season. The risk is higher in the south than in the north of the study area, and is especially high in the southwest of the study area.