The methodology and results of economic assessment and forecasting of the consequences of the most negative global climate change IPCC scenario (RCP 8.5) representative for the conditions of the Russian Arctic in the form of thawing and degradation of permafrost for healthcare facilities in eight Arctic regions of the Russian Federation are discussed. It is shown that the additional costs associated with these consequences for the maintenance and restoration of healthcare facilities in 2021-2050 may amount to about ₽60 bln, or about ₽2 bln per year (in 2021 prices) at the average rate of permafrost degradation and increase thawing depth, rising to ₽219 bln (₽7.5 bln bln annually) under the maximum expected damage.