The Guidelines cover core interventions, supplementary interventions, personal protection measures and other interventions. Core interventions for malaria vector control are applicable for all populations at risk of malaria in most epidemiological and ecological settings, namely: i) deployment of insecticide-treated nets (ITNs) that are prequalified by WHO, which in many settings are long-lasting insecticidal nets (LLINs); and ii) indoor residual spraying (IRS) with a product prequalified by WHO. Once high coverage with one core intervention has been achieved, supplementary interventions – namely the deployment of chemical or biological larvicides – can be used in addition to the core interventions in specific settings and circumstances.