Summertime ozone (O(3)) pollution has frequently occurred in the Beijing-Tianjin-Hebei (BTH) region, China, since 2013, resulting in detrimental impacts on human health and ecosystems. The contribution of weather shifts to O(3) concentration variability owing to climate change remains elusive. By combining regional air chemistry model simulations with near-surface observations, we found that anthropogenic emission changes contributed to approximately 23% of the increase in maximum daily 8-h average O(3) concentrations in the BTH region in June-July-August (JJA) 2017 (compared with that in 2013). With respect to the weather shift influence, the frequencies, durations, and magnitudes of O(3) exceedance were consistent with those of the heat wave events in the BTH region during JJA in 2013-2017. Intensified heat waves are a significant driver for worsening O(3) pollution. In particular, the prolonged duration of heat waves creates consecutive adverse weather conditions that cause O(3) accumulation and severe O(3) pollution. Our results suggest that the variability in extreme summer heat is closely related to the occurrence of high O(3) concentrations, which is a significant driver of deteriorating O(3) pollution.